The discomfort from a tummy tuck mostly comes from the muscle plication, or tightening. To help alleviate this pain, Dr. Waltzman injects a medication called Exparel into the muscles and around all of the incisions. This medication provides pain relief for up to 72 hours. You should still expect to feel tight and sore, but this medication will help to decrease your overall discomfort. You will also have access to Tylenol, ibuprofen, and a narcotic medication. Most patients are off of all pain medications by 1-2 weeks.